abstract：:The simultaneous presence of homogeneous and heterogeneous reactions at different binding sites of a multiepitope antigen makes the description of the kinetic parameters of the so called "one step" solid phase immunometric assays complex. The authors extended the "one step" approach to the concept of the "soluble sand...

journal_title：Annales de biologie clinique

authors： Chieregatti G,Massaglia A,Giraudi G,Zannino M,Barbieri U,Boniolo A

更新日期：1990-01-01 00:00:00

abstract：:Twenty-two amino acids are measured in cerebrospinal fluid of fourty patients with senile dementia of the Alzheimer type (SDAT) and of ten age matched healthy control subjects. There is no significant difference between these two groups. ...

journal_title：Annales de biologie clinique

authors： Gelot MA,Jeandel C,Belleville F,Nabet P,Penin F,Cuny G

更新日期：1990-01-01 00:00:00

abstract：:Blood histamine proved to be important for the immune homeostasis. By its direct action or by means of H-2 receptors it end or prevents the excessive immune response. Recent studies revealed changes in cell mediated immunity in subjects with atopia, with increased histaminemia and their obvious protection against canc...

journal_title：Annales de biologie clinique

authors： Stanciu L

更新日期：1990-01-01 00:00:00

abstract：:In chronic renal failure HbA1c values and plasma fructosamine concentrations are difficult to interpret owing to anaemia (for HbA1c) and analytical interferences (for fructosamine test). Plasma proteins glycation was measured more specifically by affinity chromatography. Glycated albumin, glycated immunoglobulins G an...

journal_title：Annales de biologie clinique

authors： Bordas-Fondrede M,Sauser E,Jardel C,Jaudon MC,Thervet F,Rottembourg J,Delattre J

更新日期：1990-01-01 00:00:00

abstract：:The specificity of six peroxidase-labelled anti-albumin monoclonal antibodies was studied by allowing them to react with albumin-derived fragments of known structure comprising the whole albumin molecule. The epitopes corresponding to these antibodies were located on defined regions of the albumin molecule extending f...

journal_title：Annales de biologie clinique

authors： Lapresle C

更新日期：1990-01-01 00:00:00

abstract：:The proliferation of commercial immunoassays for the determination of apolipoproteins AI and B as parameters of risk for coronary heart disease and the discordance between the values obtained with the systems have made more urgent than ever the need for standardization of these assays. The authors report here the resu...

journal_title：Annales de biologie clinique

authors： Beucler I,Caces E,Camare R,Dachet C,Fruchart JC,Gambert P,Girault A,Leglise D,Legrand A,Mainard F

更新日期：1990-01-01 00:00:00

abstract：:Lungs can be the target of many fungal parasitic organisms. Some of them are specific to the lung (Pneumocystis); while others will migrate there in the course of their life cycle (Ascaris) or be caught in it (Paragonimus, Echinococcus). Sometimes, they also generate hypersensitivity reactions (fungi). In making a dia...

journal_title：Annales de biologie clinique

authors： De Gentile L,Chabasse D

更新日期：1990-01-01 00:00:00

abstract：:Twenty four strains of coagulase-negative staphylococci from clinically significant blood cultures were separated in four groups on the basis of oxacillin susceptibility and phenotype of resistance to aminoglycoside antibiotics. Susceptibility testing included disk diffusion testing, M.I.C. and M.B.C. determinations a...

journal_title：Annales de biologie clinique

authors： Truchet A,Minet J,Mamez C,Cormier M

更新日期：1990-01-01 00:00:00

abstract：:43, patients, subjected to cervical cytology, colposcopy and colposcopic directed biopsy, were found to have lesions suggestive of human Papillomavirus (HPV) infection by one or more parameters. Immunohistochemical staining for HPV antigen yielded positive results in 23 (53.5 p. cent) cases. Amongst 30 cases with HPV ...

journal_title：Annales de biologie clinique

authors： Luthra UK,Bhatnagar P,Das DK,Sharma BK,Kashyap V,Khan IU,Singh V,Murthy NS

更新日期：1989-01-01 00:00:00

abstract：:In this report, the authors have studied the plasma and red blood cell concentrations of both zinc and copper in 90 uremic patients treated by intermittent hemodialysis. They found that plasmatic and erythrocytic levels of zinc together with the copper red blood cell concentrations determined before and after the hemo...

journal_title：Annales de biologie clinique

authors： Agenet C,Brugère CC,Reynier JP

更新日期：1989-01-01 00:00:00

abstract：:Cytofluorograph analysis after immunofluorescence with monoclonal antibodies can be useful for various antigens identification on the surface of cell membrane. This technic is described for antigen HLA B27 identification. This HLA antigen is known indeed to be linked to rhumatismal diseases. The fluorescence histogram...

journal_title：Annales de biologie clinique

authors： Fizet D,Hitte C,Ferrer AM,Vezon G

更新日期：1989-01-01 00:00:00

abstract：:Several biological parameters for assessing selenium status have been determined in years 1985-1986 in a large Belgian population group, males and females 0 to 92 years old, representative from Brussels and surroundings. In 145 people, 20 to 79 years old, mean concentrations were: 1.06 +/- 0.15 mumol Se/l plasma, 5.0 ...

journal_title：Annales de biologie clinique

authors： Neve J,Vertongen F,Peretz A,Carpentier YA

更新日期：1989-01-01 00:00:00

abstract：:Monoclonal antibodies are being used as drugs in the diagnosis, prevention, and treatment of human diseases. The discipline of antibody engineering has evolved with modern cellular and molecular biology methods to meet the challenge of producing human monoclonal antibodies for in vivo biotherapy. In this overview, app...

journal_title：Annales de biologie clinique

authors： Hamilton RG

更新日期：1989-01-01 00:00:00

abstract：:Increased level of C reactive protein in the serum of neonates indicates the presence of infection, whereas the classic signs (hyperthermia, neutrophilia...) may often fail. So the determination of C reactive protein is useful and has to be rapidly performed on a small quantity of blood. The authors evaluate a fluores...

journal_title：Annales de biologie clinique

authors： Benattar C,Francoual J,Magny JF,Lindenbaum A

更新日期：1989-01-01 00:00:00

abstract：:Precise identification and determination of MICs of clinical isolates of Acinetobacter identified to other species than the hospital species A. baumannii were carried out. On 260 Acinetobacter strains isolated in an hospital over a 6 months period, 31 strains (12 p. cent) were identified to species other than A. bauma...

journal_title：Annales de biologie clinique

authors： Freney J,Bouvet PJ,Tixier C

更新日期：1989-01-01 00:00:00

abstract：:There is no doubt that the autoimmune process in human disease depends on genetic factors. Varying associations were noticed between HLA DR and autoimmune disorders. The frequency of HLA-A-B and DR antigens as well as the Bf and C4 allotypes have been investigated in insulinodependant diabetes mellitus (IDDM) and comp...

journal_title：Annales de biologie clinique

authors： Jenhani F,Bardi R,Gorgi Y,Ayed K,Chammaki S,Boukhris R

更新日期：1989-01-01 00:00:00

abstract：:M.I.S.-Enterobacteriaceae is a new kit for identifying Enterobacteriaceae using a microplate consisting of 21 biochemical characters with automated reading and interpretation. The validity of this method was studied by the identification of 350 strains of enterobacteria belonging to 44 species and comparison with the ...

journal_title：Annales de biologie clinique

authors： Scheftel JM,Barth JG,Vincent M

更新日期：1989-01-01 00:00:00

abstract：:The authors describe an immunoassay technique of serum progesterone using a chemiluminescent tracer (LIA): progesterone aminobutylethylisoluminol 11-a-hemisuccinate (P-ABEI). The intrinsic characteristics of this technique were studied. The progesterone concentrations of 62 serum samples were simultaneously titrated u...

journal_title：Annales de biologie clinique

authors： Guilloteau D,Petat E,Besnard JC

更新日期：1988-01-01 00:00:00

abstract：:Advances in molecular biology applied to the location of genes have generated a real evolution for the screening of women carrying X-related diseases. It is however imperative to first try to define the status of these women using classical methods: bayesian calculations taking into account genealogical data and direc...

journal_title：Annales de biologie clinique

authors： Kaplan J

更新日期：1988-01-01 00:00:00

abstract：:The experience of a specialized laboratory for the biological diagnosis of inborn errors of metabolism in selected pediatrics patients is reported. The strategy starts with a wide testing of blood and urine, as many inborn errors of metabolism can be detected through testing of blood and urine for increased concentrat...

journal_title：Annales de biologie clinique

authors： Divry P,Maire I,Mathieu M

更新日期：1988-01-01 00:00:00

abstract：:Theoretical iron fixation capacity of transferrin (FCT) can be calculated on its immunochemical titration: (FCT (mumol/l = transferrin (g/l) x 25). Today, its reckoning is more advisable to serum total iron binding capacity measurement. The authors studied the effects of this new proceeding upon usual values interval ...

journal_title：Annales de biologie clinique

authors： Dezier JF,Vernet M,Damour O,Guillemin G,Le Treut A,Paris M,Plomteux G,Pressac M,Revenant MC,Rymer JC

更新日期：1988-01-01 00:00:00

abstract：:A diffuse lesion in the alveolar-capillary membrane appears as an initial pathological event which preludes the emergence of an Acute Respiratory Distress (ARDS) with pulmonary oedema. The implication of polymorphous nuclear cells (PMN) as the cells initiating this lesion remains solidly established. The activation of...

journal_title：Annales de biologie clinique

authors： Duchateau J,Lamy M

更新日期：1988-01-01 00:00:00

abstract：:The diagnosis of Protein C (PC) congenital deficiency is of first importance because it leads, more frequently than Antithrombin III deficiency, to serious thromboembolic accidents in young patients, even when PC levels are slightly decreased (40 p. cent up to 60 p. cent). In order to measure PC activity, the authors ...

journal_title：Annales de biologie clinique

authors： Nicham F,Guichaoua JF,Contant G,Martinoli JL

更新日期：1988-01-01 00:00:00

abstract：:The great diversity of methods for manganese analysis in biological materials (serum, plasma, whole blood, urine, spinal fluid and hair) reveals the difficulty in measuring extremely small quantities of this element. An examination of these methods demonstrate that the most used one is flameless atomic absorption spec...

journal_title：Annales de biologie clinique

authors： Baruthio F,Guillard O,Arnaud J,Pierre F,Zawislak R

更新日期：1988-01-01 00:00:00

abstract：:Primary cancer of the liver, especially common in inter-tropical Africa and South-East Asia, still remains inaccessible to a really effective therapy, except for a rapid surgical excision. Improvement of its particularly poor prognosis requires therefore early screening based on reliable biological markers. Following ...

journal_title：Annales de biologie clinique

authors： Deugnier Y,David V,Leray G,Blayau M,Le Gall JY

更新日期：1988-01-01 00:00:00

abstract：:The authors have studied several seric, plasmatic and urinary constituents in patients hospitalized for an acute abdominal syndrome to be able to characterize an eventual pancreatic lesion; mainly seric and urinary amylase as well as its isoenzymes, lipase, liver profile and trypsin. In acute pancreatitis, the means o...

journal_title：Annales de biologie clinique

authors： Foucault P,Menard S,Papadopoulos V,Bureau F,Travert G,Labat-Robert J,Meimon G,Siramy M,Drosdowsky M

更新日期：1988-01-01 00:00:00

abstract：:The presence, in metropolitan France, of large foreign communities originating from Maghreb and from Black Africa, introduces hereditary haemoglobinopathies diagnosis in the routine work of the clinical laboratory. On the other hand, the sustained interest of the medical staff and of biologists arises principally from...

journal_title：Annales de biologie clinique

authors： Neuzil E,Hombrados I

更新日期：1988-01-01 00:00:00

abstract：:We have compared three assays for serum galactosyltransferase activity, which use ovomucoïd, asialo agalactofetuin and free N-acetylglucosamine respectively as exogenous acceptors. A very good correlation between the three assays is obtained, for the whole range of GT activity. When the methods are compared to one ano...

journal_title：Annales de biologie clinique

authors： Bar E,Malas JP,Gauduchon P,Aubert M,Sichel F,Bedard PY,Le Talaer JY

更新日期：1988-01-01 00:00:00

abstract：:Tissue Plasminogen Activator (t-PA), Single Chain Urokinase Plasminogen Activator or pro-Urokinase (scu-PA or pro-UK) and acyl enzymes are new thrombolytic agents, characterized by a high fibrin affinity, so that they provoke only mild systemic fibrinolytic effect. Their infusion would allie good thrombolytic activity...

journal_title：Annales de biologie clinique

authors： Nguyen G,Samama M

更新日期：1987-01-01 00:00:00

abstract：:Activation of plasminogen by tissue-type plasminogen activator (tpA) is potentiated by fibrin. We have demonstrated the role of fibrin polymerization in the potentiating effect of tpA-induced fibrinolysis. Therefore a pathogenic mechanism of thrombotic disorder may be related to an abnormal fibrin polymerization: the ...

journal_title：Annales de biologie clinique

authors： Soria C,Soria J,Mirshahi M,Desvignes P,Bonnet P,Caen JP

更新日期：1987-01-01 00:00:00

abstract：:Diagnosis of systemic candidiasis is difficult and often performed lately. It can be improved by Candida antigen detection, using agglutination of latex particles sensitized with anti-Candida albicans antibody. Candida antigen search was made in 407 sera obtained from 123 patients, in Hematology and in intensive care ...

journal_title：Annales de biologie clinique

authors： Piens MA,Guyotat D,Pichot J,Mojon M

更新日期：1987-01-01 00:00:00

abstract：:Using factorial design, the authors evaluate the factors which influence in vitro, the anti-fungal activity of ketoconazole against a strain of Candida albicans (CBS 562). With the four mediums most frequently used, (Sabouraud, Casitone, MEM, YNB) they precise the results concerning inoculum, pH, incubation temperatur...

journal_title：Annales de biologie clinique

authors： Mary C,Blancard A,Goudard M,Quilici M,Regli P

更新日期：1987-01-01 00:00:00

abstract：:ATB 32 GN was tested with 279 gram negative non fastidious rods = 188 Enterobacteriaceae and 91 non-enterobacteriaceae. This micro-method included 32 carbon substrate's assimilation tests, read and interpreted automatically after incubation for one or two days at 30 degrees C. 93.5 p. cent of all bacteria are correctl...

journal_title：Annales de biologie clinique

authors： Croize J,Rouhan D,Le Noc P

更新日期：1987-01-01 00:00:00

abstract：:The in vitro activity of the broad-spectrum antifungals miconazole, ketoconazole and itraconazole was evaluated by the decimal dilution method in liquid media, for respectively 2511, 1536 and 1859 strains of yeasts belonging to 31 species. Sabouraud broth was used for miconazole and brain heart infusion broth for keto...

journal_title：Annales de biologie clinique

authors： Van Cutsem J,Van Gerven F,Janssen PA

更新日期：1987-01-01 00:00:00

abstract：:We investigated two different freezing protocols on mouse embryos that were either grown in vivo or were grown in vitro for a certain period. Our results confirm that an extended in vitro culture period makes the embryo more susceptible for injury due to freezing and thawing. Furthermore when freezing two cell mouse e...

journal_title：Annales de biologie clinique

authors： Van den Abbeel E,Van Steirteghem AC

更新日期：1987-01-01 00:00:00

abstract：:The stimulation regimens and the results of ovulation induction in anovulatory patients and in patients suffering from a Luteinized Unruptured Follicle (LUF) syndrome are discussed as well as the findings concerning superovulation in IVF cycles. The percentage of multiple pregnancies (less than or equal to 20 p. cent)...

journal_title：Annales de biologie clinique

authors： Devroey P,Wisanto A,Smitz J,Braeckmans P,Van Waesberghe L,Van Steirteghem AC

更新日期：1987-01-01 00:00:00

abstract：:Eight Capnocytophaga infections are described: bacteremia in immunodepressed patients (three cases), endocarditis (one case), pneumopathy (one case), buccal infection (two cases) and endometritis during use of an intrauterine contraceptive device (one case). The role of this bacterium in infections presented by immuno...

journal_title：Annales de biologie clinique

authors： Arlet G,Sanson-Le Pors MJ,Ortenberg M,Felten A,Perol Y

更新日期：1986-01-01 00:00:00

abstract：:Beyond persistent underestimation of atherogenic dyslipoproteinemias of genetic origin, which account altogether for one out of 50 births, and even more, considerable advances have been done, in the last past years, about molecular and genetic basis of metabolic defects, and possible various mutations--at this level. ...

journal_title：Annales de biologie clinique

authors： de Gennes JL

更新日期：1986-01-01 00:00:00

abstract：:Sixty-three strains of Pseudomonas paucimobilis, a Gram-negative, lemon yellow pigmented, glucose nonfermenting bacillus are phenotypically compared to the type strain of this new species (ATCC 29837). The morphological, cultural, biochemical (ONPG-test, oxidase, aesculin positive) and nutritional (assimilation of man...

journal_title：Annales de biologie clinique

authors： Richard C

更新日期：1986-01-01 00:00:00

abstract：:High performance liquid chromatography has been used to separate and analyse the different free porphyrins in biological materials. The selective determination of uroporphyrin, coproporphyrin, protoporphyrin and hepta, hexa, pentacarboxylic porphyrins, the sensitive and quantitative fluorescence detection contribute t...

journal_title：Annales de biologie clinique

authors： Richard MJ,Fovet B,Fontaine M,Boersma A

更新日期：1986-01-01 00:00:00